Solinas, Giovanni <br/><br/>
Saturated fatty acids inhibit induction of insulin gene transcription by JNK-mediated phosphorylation of insulin-receptor substrates.  [electronic resource] 

 -  Proceedings of the National Academy of Sciences of the United States of America  Oct 2006 
 - 16454-9 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0027-8424 
<br/><br/><label>Standard No.: </label>10.1073/pnas.0607626103  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acid Sequence<br/>Animals<br/>Blood Glucose--metabolism<br/>Cells, Cultured<br/>Enzyme Activation<br/>Fatty Acids--metabolism<br/>Gene Expression Regulation<br/>Hepatocytes--drug effects<br/>Humans<br/>Insulin--genetics<br/>Insulin Receptor Substrate Proteins<br/>Insulin Resistance<br/>Intracellular Signaling Peptides and Proteins--chemistry<br/>Male<br/>Mice<br/>Mitogen-Activated Protein Kinase 8--deficiency<br/>Obesity--metabolism<br/>Palmitic Acid--pharmacology<br/>Phosphoproteins--chemistry<br/>Phosphorylation<br/>Rats<br/>Substrate Specificity<br/>Transcription, Genetic--genetics