TY - GEN AU - Hur,Jingyung AU - Bell,Daphne W AU - Dean,Kathleen L AU - Coser,Kathryn R AU - Hilario,Pablo C AU - Okimoto,Ross A AU - Tobey,Erica M AU - Smith,Shannon L AU - Isselbacher,Kurt J AU - Shioda,Toshi TI - Regulation of expression of BIK proapoptotic protein in human breast cancer cells: p53-dependent induction of BIK mRNA by fulvestrant and proteasomal degradation of BIK protein SN - 0008-5472 PY - 2006///1204 KW - Antineoplastic Agents KW - pharmacology KW - Antineoplastic Agents, Hormonal KW - Apoptosis Regulatory Proteins KW - biosynthesis KW - Breast Neoplasms KW - drug therapy KW - Cell Line, Tumor KW - Doxorubicin KW - Estradiol KW - analogs & derivatives KW - Fulvestrant KW - Gamma Rays KW - Gene Expression Regulation, Neoplastic KW - drug effects KW - Humans KW - Leupeptins KW - Membrane Proteins KW - Mitochondrial Proteins KW - Promoter Regions, Genetic KW - Proteasome Endopeptidase Complex KW - metabolism KW - Proteasome Inhibitors KW - RNA, Messenger KW - Receptors, Estrogen KW - Transcription, Genetic KW - Tumor Suppressor Protein p53 KW - genetics N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/0008-5472.CAN-05-3696 ER -