Saydoff, Joel A
Oral uridine pro-drug PN401 is neuroprotective in the R6/2 and N171-82Q mouse models of Huntington's disease. [electronic resource]
- Neurobiology of disease Dec 2006
- 455-65 p. digital
Publication Type: Comparative Study; Journal Article
ISSN: 0969-9961
Standard No.: 10.1016/j.nbd.2006.08.011 doi
Subjects--Topical Terms: Acetates Administration, Oral Analysis of Variance Animals Cerebral Cortex--cytology Disease Models, Animal Female Huntingtin Protein Huntington Disease--drug therapy Male Mice Mice, Inbred C3H Mice, Inbred C57BL Mice, Neurologic Mutants Mice, Transgenic Motor Activity--drug effects Neostriatum--cytology Nerve Degeneration--drug therapy Nerve Tissue Proteins--drug effects Neuroprotective Agents--pharmacology Nuclear Proteins--drug effects Prodrugs--pharmacology Rotarod Performance Test Uridine--administration & dosage