Saydoff, Joel A

Oral uridine pro-drug PN401 is neuroprotective in the R6/2 and N171-82Q mouse models of Huntington's disease. [electronic resource] - Neurobiology of disease Dec 2006 - 455-65 p. digital

Publication Type: Comparative Study; Journal Article

0969-9961

10.1016/j.nbd.2006.08.011 doi


Acetates
Administration, Oral
Analysis of Variance
Animals
Cerebral Cortex--cytology
Disease Models, Animal
Female
Huntingtin Protein
Huntington Disease--drug therapy
Male
Mice
Mice, Inbred C3H
Mice, Inbred C57BL
Mice, Neurologic Mutants
Mice, Transgenic
Motor Activity--drug effects
Neostriatum--cytology
Nerve Degeneration--drug therapy
Nerve Tissue Proteins--drug effects
Neuroprotective Agents--pharmacology
Nuclear Proteins--drug effects
Prodrugs--pharmacology
Rotarod Performance Test
Uridine--administration & dosage