TY  - GEN
AU  - Levy,Aharon
AU  - Cohen,Giora
AU  - Gilat,Eran
AU  - Kapon,Joseph
AU  - Dachir,Shlomit
AU  - Abraham,Shlomo
AU  - Herskovitz,Miriam
AU  - Teitelbaum,Zvi
AU  - Raveh,Lily
TI  - Extrapolating from animal studies to the efficacy in humans of a pretreatment combination against organophosphate poisoning
SN  - 0340-5761
PY  - 2007///1009
KW  - Animals
KW  - Chemical Warfare Agents
KW  - poisoning
KW  - Cholinergic Antagonists
KW  - administration & dosage
KW  - Cyclopentanes
KW  - blood
KW  - Disease Models, Animal
KW  - Dogs
KW  - Dose-Response Relationship, Drug
KW  - Drug Evaluation, Preclinical
KW  - methods
KW  - Drug Therapy, Combination
KW  - Female
KW  - Humans
KW  - Infusions, Intravenous
KW  - Infusions, Parenteral
KW  - Lethal Dose 50
KW  - Male
KW  - Metabolic Clearance Rate
KW  - Organophosphate Poisoning
KW  - Organophosphates
KW  - Papio anubis
KW  - Poisoning
KW  - Pyridostigmine Bromide
KW  - Sarin
KW  - Species Specificity
KW  - Treatment Outcome
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1007/s00204-006-0153-6
ER  -