TY  - GEN
AU  - Schittenhelm,M M
AU  - Yee,K W H
AU  - Tyner,J W
AU  - McGreevey,L
AU  - Haley,A D
AU  - Town,A
AU  - Griffith,D J
AU  - Bainbridge,T
AU  - Braziel,R M
AU  - O'Farrell,A-M
AU  - Cherrington,J M
AU  - Heinrich,M C
TI  - FLT3 K663Q is a novel AML-associated oncogenic kinase: Determination of biochemical properties and sensitivity to Sunitinib (SU11248)
SN  - 0887-6924
PY  - 2006///1205
KW  - Acute Disease
KW  - Amino Acid Sequence
KW  - Amino Acid Substitution
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Apoptosis
KW  - drug effects
KW  - Base Sequence
KW  - Cell Division
KW  - Cell Line, Tumor
KW  - Humans
KW  - Indoles
KW  - Leukemia, Myeloid
KW  - drug therapy
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Mice, Nude
KW  - Mutagenesis, Site-Directed
KW  - Neoplasm Transplantation
KW  - Point Mutation
KW  - Pyrroles
KW  - Sunitinib
KW  - fms-Like Tyrosine Kinase 3
KW  - genetics
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1038/sj.leu.2404374
ER  -