TY  - GEN
AU  - Kumar,Santosh
AU  - Liu,Hong
AU  - Halpert,James R
TI  - Engineering of cytochrome P450 3A4 for enhanced peroxide-mediated substrate oxidation using directed evolution and site-directed mutagenesis
SN  - 0090-9556
PY  - 2007///0212
KW  - Benzene Derivatives
KW  - chemistry
KW  - Coumarins
KW  - metabolism
KW  - Cytochrome P-450 CYP3A
KW  - genetics
KW  - Directed Molecular Evolution
KW  - Hydrogen Peroxide
KW  - Mutagenesis, Site-Directed
KW  - Oxidation-Reduction
KW  - Quinolines
KW  - Testosterone
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1124/dmd.106.012054
ER  -