TY  - GEN
AU  - Mukherjee,Odity
AU  - Pastor,Pau
AU  - Cairns,Nigel J
AU  - Chakraverty,Sumi
AU  - Kauwe,John S K
AU  - Shears,Shantia
AU  - Behrens,Maria I
AU  - Budde,John
AU  - Hinrichs,Anthony L
AU  - Norton,Joanne
AU  - Levitch,Denise
AU  - Taylor-Reinwald,Lisa
AU  - Gitcho,Michael
AU  - Tu,P-H
AU  - Tenenholz Grinberg,Lea
AU  - Liscic,Rajka M
AU  - Armendariz,Javier
AU  - Morris,John C
AU  - Goate,Alison M
TI  - HDDD2 is a familial frontotemporal lobar degeneration with ubiquitin-positive, tau-negative inclusions caused by a missense mutation in the signal peptide of progranulin
SN  - 0364-5134
PY  - 2006///1114
KW  - Adult
KW  - Aged
KW  - Aged, 80 and over
KW  - Aspartic Acid
KW  - genetics
KW  - Chromosomes, Human, Pair 17
KW  - DNA Mutational Analysis
KW  - methods
KW  - Dementia
KW  - Family Health
KW  - Female
KW  - Genetic Predisposition to Disease
KW  - Humans
KW  - Immunohistochemistry
KW  - Inclusion Bodies
KW  - metabolism
KW  - Intercellular Signaling Peptides and Proteins
KW  - Male
KW  - Middle Aged
KW  - Mutation, Missense
KW  - Neuropsychological Tests
KW  - statistics & numerical data
KW  - Ubiquitin
KW  - Valine
KW  - tau Proteins
N1  - Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1002/ana.20963
ER  -