TY - GEN AU - Wadelius,M AU - Pirmohamed,M TI - Pharmacogenetics of warfarin: current status and future challenges SN - 1470-269X PY - 2007///0620 KW - Anticoagulants KW - administration & dosage KW - Aryl Hydrocarbon Hydroxylases KW - genetics KW - Biotransformation KW - Cytochrome P-450 CYP2C9 KW - Gene Expression Regulation, Enzymologic KW - Genetic Predisposition to Disease KW - Genotype KW - Hemorrhage KW - chemically induced KW - Humans KW - Liver KW - drug effects KW - Mixed Function Oxygenases KW - Patient Selection KW - Polymorphism, Single Nucleotide KW - Treatment Outcome KW - Vitamin K KW - antagonists & inhibitors KW - Vitamin K Epoxide Reductases KW - Warfarin N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review UR - https://doi.org/10.1038/sj.tpj.6500417 ER -