TY - GEN AU - Young,Robert J AU - Campbell,Matthew AU - Borthwick,Alan D AU - Brown,David AU - Burns-Kurtis,Cynthia L AU - Chan,Chuen AU - Convery,Máire A AU - Crowe,Miriam C AU - Dayal,Satish AU - Diallo,Hawa AU - Kelly,Henry A AU - King,N Paul AU - Kleanthous,Savvas AU - Mason,Andrew M AU - Mordaunt,Jackie E AU - Patel,Champa AU - Pateman,Anthony J AU - Senger,Stefan AU - Shah,Gita P AU - Smith,Paul W AU - Watson,Nigel S AU - Weston,Helen E AU - Zhou,Ping TI - Structure- and property-based design of factor Xa inhibitors: pyrrolidin-2-ones with acyclic alanyl amides as P4 motifs SN - 0960-894X PY - 2007///0108 KW - Alanine KW - chemistry KW - Amides KW - Anticoagulants KW - chemical synthesis KW - Antithrombin III KW - Binding Sites KW - Crystallography, X-Ray KW - Drug Design KW - Factor Xa KW - Models, Molecular KW - Molecular Structure KW - Pyrroles KW - Structure-Activity Relationship N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.bmcl.2006.09.001 ER -