TY  - GEN
AU  - Fernandez-Gomez,F J
AU  - Pastor,M D
AU  - Garcia-Martinez,E M
AU  - Melero-Fernandez de Mera,R
AU  - Gou-Fabregas,M
AU  - Gomez-Lazaro,M
AU  - Calvo,S
AU  - Soler,R M
AU  - Galindo,M F
AU  - Jordán,J
TI  - Pyruvate protects cerebellar granular cells from 6-hydroxydopamine-induced cytotoxicity by activating the Akt signaling pathway and increasing glutathione peroxidase expression
SN  - 0969-9961
PY  - 2007///0123
KW  - Animals
KW  - Animals, Newborn
KW  - Antioxidants
KW  - metabolism
KW  - Apoptosis
KW  - drug effects
KW  - Cells, Cultured
KW  - Cerebellar Cortex
KW  - Cytoprotection
KW  - Dose-Response Relationship, Drug
KW  - Extracellular Signal-Regulated MAP Kinases
KW  - Glutathione Peroxidase
KW  - Lipid Peroxidation
KW  - Nerve Degeneration
KW  - drug therapy
KW  - Neurons
KW  - Neuroprotective Agents
KW  - Neurotoxins
KW  - antagonists & inhibitors
KW  - Oxidative Stress
KW  - Oxidopamine
KW  - Phosphatidylinositol 3-Kinases
KW  - Phosphoinositide-3 Kinase Inhibitors
KW  - Proto-Oncogene Proteins c-akt
KW  - Pyruvic Acid
KW  - RNA, Messenger
KW  - Rats
KW  - Signal Transduction
KW  - Up-Regulation
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.nbd.2006.07.005
ER  -