Mueller, Steffen

Reduction of the rate of poliovirus protein synthesis through large-scale codon deoptimization causes attenuation of viral virulence by lowering specific infectivity. [electronic resource] - Journal of virology Oct 2006 - 9687-96 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

0022-538X

10.1128/JVI.00738-06 doi


Animals
Capsid Proteins--genetics
Codon--genetics
Enzyme-Linked Immunosorbent Assay
Genome, Viral--genetics
HeLa Cells
Humans
Membrane Proteins--genetics
Mice
Mice, Transgenic
Phenotype
Poliomyelitis--genetics
Poliovirus--genetics
Protein Biosynthesis--genetics
Receptors, Virus--genetics
Virulence--genetics