Popik, Piotr <br/><br/>
The anxioselective agent 7-(2-chloropyridin-4-yl)pyrazolo-[1,5-a]-pyrimidin-3-yl](pyridin-2-yl)methanone (DOV 51892) is more efficacious than diazepam at enhancing GABA-gated currents at alpha1 subunit-containing GABAA receptors.  [electronic resource] 

 -  The Journal of pharmacology and experimental therapeutics  Dec 2006 
 - 1244-52 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0022-3565 
<br/><br/><label>Standard No.: </label>10.1124/jpet.106.107201  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Anti-Anxiety Agents--chemical synthesis<br/>Ataxia--chemically induced<br/>Chloride Channels--drug effects<br/>Diazepam--pharmacology<br/>Dose-Response Relationship, Drug<br/>Exploratory Behavior--drug effects<br/>Hand Strength--physiology<br/>Hypnotics and Sedatives--pharmacology<br/>Male<br/>Motor Activity--drug effects<br/>Muscle Relaxation--drug effects<br/>Oocytes--metabolism<br/>Postural Balance--drug effects<br/>Pyrazoles--chemical synthesis<br/>Pyridines--chemical synthesis<br/>Radioligand Assay<br/>Rats<br/>Rats, Sprague-Dawley<br/>Rats, Wistar<br/>Receptors, GABA-A--drug effects<br/>Xenopus laevis<br/>gamma-Aminobutyric Acid--physiology