TY  - GEN
AU  - James,Jehana
AU  - Murry,Daryl J
AU  - Treston,Anthony M
AU  - Storniolo,Anna Maria
AU  - Sledge,George W
AU  - Sidor,Carolyn
AU  - Miller,Kathy D
TI  - Phase I safety, pharmacokinetic and pharmacodynamic studies of 2-methoxyestradiol alone or in combination with docetaxel in patients with locally recurrent or metastatic breast cancer
SN  - 0167-6997
PY  - 2007///0205
KW  - 2-Methoxyestradiol
KW  - Administration, Oral
KW  - Adult
KW  - Aged
KW  - Antineoplastic Agents, Phytogenic
KW  - administration & dosage
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - adverse effects
KW  - Area Under Curve
KW  - Breast Neoplasms
KW  - drug therapy
KW  - Docetaxel
KW  - Drug Administration Schedule
KW  - Estradiol
KW  - Fatigue
KW  - chemically induced
KW  - Female
KW  - Half-Life
KW  - Humans
KW  - Matrix Metalloproteinase 2
KW  - blood
KW  - Matrix Metalloproteinase 9
KW  - Middle Aged
KW  - Neoplasm Metastasis
KW  - Neoplasm Recurrence, Local
KW  - Taxoids
KW  - Treatment Outcome
KW  - Tubulin Modulators
KW  - Urinalysis
KW  - Vascular Cell Adhesion Molecule-1
KW  - Vascular Endothelial Growth Factor A
KW  - urine
N1  - Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1007/s10637-006-9008-5
ER  -