TY - GEN AU - Jacinto,Estela AU - Facchinetti,Valeria AU - Liu,Dou AU - Soto,Nelyn AU - Wei,Shiniu AU - Jung,Sung Yun AU - Huang,Qiaojia AU - Qin,Jun AU - Su,Bing TI - SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity SN - 0092-8674 PY - 2006///1218 KW - Adaptor Proteins, Signal Transducing KW - genetics KW - Animals KW - Carrier Proteins KW - Cells, Cultured KW - Fibroblasts KW - cytology KW - Forkhead Box Protein O1 KW - Forkhead Box Protein O3 KW - Forkhead Transcription Factors KW - Gene Silencing KW - Humans KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Multiprotein Complexes KW - Phosphoproteins KW - Phosphorylation KW - Protein Kinases KW - Proteins KW - Proto-Oncogene Proteins c-akt KW - Rapamycin-Insensitive Companion of mTOR Protein KW - Regulatory-Associated Protein of mTOR KW - Signal Transduction KW - physiology KW - Substrate Specificity KW - TOR Serine-Threonine Kinases KW - Threonine KW - metabolism KW - Transcription Factors N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.cell.2006.08.033 ER -