Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin. [electronic resource]
- Molecular and cellular biochemistry Feb 2007
- 85-95 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
0300-8177
10.1007/s11010-006-9302-8 doi
ATP Binding Cassette Transporter, Subfamily B ATP Binding Cassette Transporter, Subfamily B, Member 1 ATP Binding Cassette Transporter, Subfamily G, Member 2 ATP-Binding Cassette Transporters--metabolism Adenosine Triphosphate--metabolism Antineoplastic Agents--chemistry Beryllium--metabolism Cell Line, Tumor Chlorophyll--analogs & derivatives Curcumin--analogs & derivatives Drug Resistance, Multiple--physiology Drug Resistance, Neoplasm Etoposide--metabolism Fluoresceins--metabolism Fluorescent Dyes--metabolism Fluorides--metabolism Humans Mitoxantrone--metabolism Molecular Structure Multidrug Resistance-Associated Proteins--metabolism Neoplasm Proteins--metabolism Organic Anion Transporters--metabolism Rhodamine 123--metabolism Vinblastine--metabolism