Watanabe, Daiya <br/><br/>
Quantitative evaluation of each catalytic subsite of cathepsin B for inhibitory activity based on inhibitory activity-binding mode relationship of epoxysuccinyl inhibitors by X-ray crystal structure analyses of complexes.  [electronic resource] 

 -  Journal of molecular biology  Oct 2006 
 - 979-93 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-2836 
<br/><br/><label>Standard No.: </label>10.1016/j.jmb.2006.07.070  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Binding Sites<br/>Cathepsin B--chemistry<br/>Cattle<br/>Crystallography, X-Ray<br/>Cysteine Proteinase Inhibitors--chemical synthesis<br/>Drug Design<br/>Epoxy Compounds<br/>Hydrogen Bonding<br/>Hydrophobic and Hydrophilic Interactions<br/>Inhibitory Concentration 50<br/>Models, Molecular<br/>Molecular Structure<br/>Protein Conformation<br/>Protein Structure, Secondary<br/>Static Electricity<br/>Structure-Activity Relationship<br/>Substrate Specificity<br/>Succinic Acid