TY  - GEN
AU  - El Abdellaoui,Hassan
AU  - Varaprasad,Chamakura V N S
AU  - Barawkar,Dinesh
AU  - Chakravarty,Subrata
AU  - Maderna,Andreas
AU  - Tam,Robert
AU  - Chen,Huanming
AU  - Allan,Matt
AU  - Wu,Jim Z
AU  - Appleby,Todd
AU  - Yan,Shunqi
AU  - Zhang,Weijian
AU  - Lang,Stanley
AU  - Yao,Nanhua
AU  - Hamatake,Robert
AU  - Hong,Zhi
TI  - Identification of isothiazole-4-carboxamidines derivatives as a novel class of allosteric MEK1 inhibitors
SN  - 0960-894X
PY  - 2006///1222
KW  - Allosteric Regulation
KW  - Amidines
KW  - chemical synthesis
KW  - Animals
KW  - MAP Kinase Kinase 1
KW  - antagonists & inhibitors
KW  - MAP Kinase Kinase 2
KW  - Rats
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2006.08.048
ER  -