Impact of EGFR point mutations on the sensitivity to gefitinib: insights from comparative structural analyses and molecular dynamics simulations. [electronic resource]
- Proteins Nov 2006
- 331-46 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1097-0134
10.1002/prot.21111 doi
Adenosine Triphosphate--chemistry Binding Sites Computational Biology Computer Simulation Crystallography, X-Ray ErbB Receptors--chemistry Gefitinib Ligands Models, Molecular Point Mutation--genetics Protein Structure, Secondary Protein Structure, Tertiary Proto-Oncogene Proteins c-abl--chemistry Quinazolines--chemistry Static Electricity