TY - GEN AU - Shah,O Jameel AU - Hunter,Tony TI - Turnover of the active fraction of IRS1 involves raptor-mTOR- and S6K1-dependent serine phosphorylation in cell culture models of tuberous sclerosis SN - 0270-7306 PY - 2006///0925 KW - Adaptor Proteins, Signal Transducing KW - Animals KW - Cell Culture Techniques KW - Cells, Cultured KW - Humans KW - Insulin Receptor Substrate Proteins KW - Mice KW - Monomeric GTP-Binding Proteins KW - metabolism KW - Neuropeptides KW - Phosphoproteins KW - deficiency KW - Phosphoserine KW - Protein Kinases KW - Proteins KW - Ras Homolog Enriched in Brain Protein KW - Regulatory-Associated Protein of mTOR KW - Ribosomal Protein S6 Kinases KW - Subcellular Fractions KW - TOR Serine-Threonine Kinases KW - Tuberous Sclerosis KW - pathology KW - Tuberous Sclerosis Complex 1 Protein KW - Tuberous Sclerosis Complex 2 Protein KW - Tumor Suppressor Proteins N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1128/MCB.01254-05 ER -