Soma, M R

Simvastatin, an inhibitor of cholesterol biosynthesis, shows a synergistic effect with N,N'-bis(2-chloroethyl)-N-nitrosourea and beta-interferon on human glioma cells. [electronic resource] - Cancer research Aug 1992 - 4348-55 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0008-5472


Anticholesteremic Agents--pharmacology
Carmustine--pharmacology
Cell Count--drug effects
Cell Division--drug effects
Culture Media--chemistry
Dose-Response Relationship, Drug
Drug Synergism
Glioma--drug therapy
Humans
Hydroxymethylglutaryl CoA Reductases--metabolism
Interferon-beta--pharmacology
Lovastatin--analogs & derivatives
Simvastatin
Tumor Cells, Cultured