Simvastatin, an inhibitor of cholesterol biosynthesis, shows a synergistic effect with N,N'-bis(2-chloroethyl)-N-nitrosourea and beta-interferon on human glioma cells. [electronic resource]
- Cancer research Aug 1992
- 4348-55 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0008-5472
Anticholesteremic Agents--pharmacology Carmustine--pharmacology Cell Count--drug effects Cell Division--drug effects Culture Media--chemistry Dose-Response Relationship, Drug Drug Synergism Glioma--drug therapy Humans Hydroxymethylglutaryl CoA Reductases--metabolism Interferon-beta--pharmacology Lovastatin--analogs & derivatives Simvastatin Tumor Cells, Cultured