Bartolucci, Cecilia <br/><br/>
Structural determinants of Torpedo californica acetylcholinesterase inhibition by the novel and orally active carbamate based anti-alzheimer drug ganstigmine (CHF-2819).  [electronic resource] 

 -  Journal of medicinal chemistry  Aug 2006 
 - 5051-8 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm060293s  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acetylcholinesterase--chemistry<br/>Administration, Oral<br/>Alkaloids--administration & dosage<br/>Alzheimer Disease--drug therapy<br/>Animals<br/>Binding Sites--drug effects<br/>Brain--enzymology<br/>Carbamates--administration & dosage<br/>Cholinesterase Inhibitors--administration & dosage<br/>Crystallization<br/>Crystallography, X-Ray<br/>Drug Evaluation, Preclinical<br/>Enzyme Activation--drug effects<br/>Male<br/>Mice<br/>Models, Molecular<br/>Molecular Conformation<br/>Stereoisomerism<br/>Structure-Activity Relationship<br/>Torpedo