TY - GEN AU - Kiaei,Mahmoud AU - Kipiani,Khatuna AU - Petri,Susanne AU - Chen,Junyu AU - Calingasan,Noel Y AU - Beal,M Flint TI - Celastrol blocks neuronal cell death and extends life in transgenic mouse model of amyotrophic lateral sclerosis SN - 1660-2854 PY - 2006///0920 KW - Amyotrophic Lateral Sclerosis KW - drug therapy KW - Animals KW - Astrocytes KW - drug effects KW - CD40 Antigens KW - metabolism KW - Cell Count KW - Cell Death KW - Female KW - Fluorescent Antibody Technique, Indirect KW - Glial Fibrillary Acidic Protein KW - HSP70 Heat-Shock Proteins KW - Longevity KW - Mice KW - Mice, Transgenic KW - Motor Neurons KW - Neuroglia KW - Neurons KW - Neuroprotective Agents KW - pharmacology KW - Pentacyclic Triterpenes KW - Postural Balance KW - Psychomotor Performance KW - Superoxide Dismutase KW - genetics KW - Superoxide Dismutase-1 KW - Survival Analysis KW - Triterpenes KW - Tumor Necrosis Factor-alpha KW - Up-Regulation N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1159/000090364 ER -