A Src homology 3-binding sequence on the C terminus of Sprouty2 is necessary for inhibition of the Ras/ERK pathway downstream of fibroblast growth factor receptor stimulation. [electronic resource]
- The Journal of biological chemistry Oct 2006
- 29993-30000 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
0021-9258
10.1074/jbc.M604044200 doi
Animals Cell Line Extracellular Signal-Regulated MAP Kinases--antagonists & inhibitors Humans Intracellular Signaling Peptides and Proteins Membrane Proteins PC12 Cells Peptide Fragments--physiology Phosphorylation Protein Binding Proteins--physiology Rats Receptors, Fibroblast Growth Factor--physiology Signal Transduction--physiology ras Proteins--antagonists & inhibitors src Homology Domains--physiology