Smith, Leon <br/><br/>
Novel tricyclic azepine derivatives: Biological evaluation of pyrimido[4,5-b]-1,4-benzoxazepines, thiazepines, and diazepines as inhibitors of the epidermal growth factor receptor tyrosine kinase.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Oct 2006 
 - 5102-6 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0960-894X 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2006.07.031  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--chemical synthesis<br/>Azepines--chemical synthesis<br/>Cell Line, Tumor<br/>ErbB Receptors--antagonists & inhibitors<br/>Heterocyclic Compounds, 3-Ring--chemical synthesis<br/>Humans<br/>Inhibitory Concentration 50<br/>Neoplasm Proteins--antagonists & inhibitors<br/>Phosphorylation--drug effects<br/>Structure-Activity Relationship<br/>Vascular Endothelial Growth Factor Receptor-2--antagonists & inhibitors