TY - GEN AU - Palmer,Brian D AU - Thompson,Andrew M AU - Booth,R John AU - Dobrusin,Ellen M AU - Kraker,Alan J AU - Lee,Ho H AU - Lunney,Elizabeth A AU - Mitchell,Lorna H AU - Ortwine,Daniel F AU - Smaill,Jeff B AU - Swan,Leesa M AU - Denny,William A TI - 4-Phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione inhibitors of the checkpoint kinase Wee1. Structure-activity relationships for chromophore modification and phenyl ring substitution SN - 0022-2623 PY - 2006///0913 KW - Benzene Derivatives KW - chemical synthesis KW - Carbazoles KW - Cell Cycle Proteins KW - antagonists & inhibitors KW - Checkpoint Kinase 1 KW - Crystallography, X-Ray KW - Humans KW - Models, Molecular KW - Nuclear Proteins KW - Protein Binding KW - Protein Kinases KW - chemistry KW - Protein-Tyrosine Kinases KW - Pyrroles KW - Structure-Activity Relationship N1 - Publication Type: Journal Article UR - https://doi.org/10.1021/jm0512591 ER -