Palmer, Brian D <br/><br/>
4-Phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione inhibitors of the checkpoint kinase Wee1. Structure-activity relationships for chromophore modification and phenyl ring substitution.  [electronic resource] 

 -  Journal of medicinal chemistry  Aug 2006 
 - 4896-911 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm0512591  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Benzene Derivatives--chemical synthesis<br/>Carbazoles--chemical synthesis<br/>Cell Cycle Proteins--antagonists & inhibitors<br/>Checkpoint Kinase 1<br/>Crystallography, X-Ray<br/>Humans<br/>Models, Molecular<br/>Nuclear Proteins--antagonists & inhibitors<br/>Protein Binding<br/>Protein Kinases--chemistry<br/>Protein-Tyrosine Kinases--antagonists & inhibitors<br/>Pyrroles--chemical synthesis<br/>Structure-Activity Relationship