The G-quadruplex ligand telomestatin inhibits POT1 binding to telomeric sequences in vitro and induces GFP-POT1 dissociation from telomeres in human cells. [electronic resource]
- Cancer research Jul 2006
- 6908-12 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0008-5472
10.1158/0008-5472.CAN-06-1581 doi
Cell Line DNA--biosynthesis G-Quadruplexes Green Fluorescent Proteins--genetics Humans Kidney--cytology Nuclear Proteins--metabolism Oxazoles--pharmacology Protein Binding Recombinant Fusion Proteins--genetics Shelterin Complex TATA Box Binding Protein-Like Proteins--metabolism Telomere--genetics Telomere-Binding Proteins--antagonists & inhibitors Telomeric Repeat Binding Protein 2 Transfection