TY - GEN AU - Nyunoya,Toru AU - Monick,Martha M AU - Klingelhutz,Aloysius AU - Yarovinsky,Timur O AU - Cagley,Jeffrey R AU - Hunninghake,Gary W TI - Cigarette smoke induces cellular senescence SN - 1044-1549 PY - 2007///0103 KW - Ataxia Telangiectasia Mutated Proteins KW - Cell Cycle KW - drug effects KW - Cell Cycle Proteins KW - metabolism KW - Cell Line KW - Cell Proliferation KW - Cell Shape KW - Cellular Senescence KW - Cyclin-Dependent Kinase Inhibitor p16 KW - Cyclin-Dependent Kinase Inhibitor p21 KW - DNA-Binding Proteins KW - Dose-Response Relationship, Drug KW - Fibroblasts KW - cytology KW - Humans KW - Lung KW - Phenotype KW - Phosphorylation KW - Protein Serine-Threonine Kinases KW - Pulmonary Disease, Chronic Obstructive KW - chemically induced KW - Retinoblastoma Protein KW - Smoke KW - adverse effects KW - Time Factors KW - Nicotiana KW - Tumor Suppressor Protein p53 KW - Tumor Suppressor Proteins KW - beta-Galactosidase N1 - Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1165/rcmb.2006-0169OC ER -