TY - GEN AU - Rice,Todd W AU - Wheeler,Arthur P AU - Morris,Peter E AU - Paz,Harold L AU - Russell,James A AU - Edens,Tonya R AU - Bernard,Gordon R TI - Safety and efficacy of affinity-purified, anti-tumor necrosis factor-alpha, ovine fab for injection (CytoFab) in severe sepsis SN - 0090-3493 PY - 2006///0929 KW - Animals KW - Antibodies KW - blood KW - Bronchoalveolar Lavage Fluid KW - chemistry KW - Double-Blind Method KW - Female KW - Humans KW - Immunoglobulin Fab Fragments KW - therapeutic use KW - Immunologic Factors KW - Infusions, Intravenous KW - Intensive Care Units KW - statistics & numerical data KW - Interleukin-6 KW - analysis KW - Male KW - Middle Aged KW - Prospective Studies KW - Respiration, Artificial KW - Sepsis KW - drug therapy KW - Sheep KW - immunology KW - Tumor Necrosis Factor-alpha N1 - Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Comment UR - https://doi.org/10.1097/01.CCM.0000230385.82679.34 ER -