TY - GEN AU - Cooper,Antony A AU - Gitler,Aaron D AU - Cashikar,Anil AU - Haynes,Cole M AU - Hill,Kathryn J AU - Bhullar,Bhupinder AU - Liu,Kangning AU - Xu,Kexiang AU - Strathearn,Katherine E AU - Liu,Fang AU - Cao,Songsong AU - Caldwell,Kim A AU - Caldwell,Guy A AU - Marsischky,Gerald AU - Kolodner,Richard D AU - Labaer,Joshua AU - Rochet,Jean-Christophe AU - Bonini,Nancy M AU - Lindquist,Susan TI - Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models SN - 1095-9203 PY - 2006///0731 KW - Animals KW - Animals, Genetically Modified KW - Caenorhabditis elegans KW - Cell Survival KW - Cells, Cultured KW - Disease Models, Animal KW - Dopamine KW - physiology KW - Drosophila KW - Endoplasmic Reticulum KW - metabolism KW - Gene Expression KW - Gene Library KW - Golgi Apparatus KW - Humans KW - Mice KW - Nerve Degeneration KW - Neurons KW - cytology KW - Parkinsonian Disorders KW - Proteasome Endopeptidase Complex KW - Protein Folding KW - Protein Transport KW - Proteins KW - chemistry KW - Rats KW - Recombinant Fusion Proteins KW - Saccharomyces cerevisiae KW - genetics KW - Saccharomyces cerevisiae Proteins KW - alpha-Synuclein KW - rab GTP-Binding Proteins KW - rab1 GTP-Binding Proteins N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1126/science.1129462 ER -