TY  - GEN
AU  - Sabat,Mark
AU  - Vanrens,John C
AU  - Brugel,Todd A
AU  - Maier,Jennifer
AU  - Laufersweiler,Matthew J
AU  - Golebiowski,Adam
AU  - De,Biswanath
AU  - Easwaran,Vijayasurian
AU  - Hsieh,Lily C
AU  - Rosegen,Jeff
AU  - Berberich,Steve
AU  - Suchanek,Eric
AU  - Janusz,Michael J
TI  - The development of novel 1,2-dihydro-pyrimido[4,5-c]pyridazine based inhibitors of lymphocyte specific kinase (Lck)
SN  - 0960-894X
PY  - 2006///1006
KW  - Drug Design
KW  - Drug Industry
KW  - methods
KW  - Enzyme Inhibitors
KW  - chemistry
KW  - Humans
KW  - Inhibitory Concentration 50
KW  - Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
KW  - antagonists & inhibitors
KW  - Lymphocytes
KW  - metabolism
KW  - Models, Chemical
KW  - Models, Molecular
KW  - Pyridazines
KW  - Pyrimidines
KW  - Ribonucleosides
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2006.05.072
ER  -