Inamoto, Teruo <br/><br/>
Anti-CD26 monoclonal antibody-mediated G1-S arrest of human renal clear cell carcinoma Caki-2 is associated with retinoblastoma substrate dephosphorylation, cyclin-dependent kinase 2 reduction, p27(kip1) enhancement, and disruption of binding to the extracellular matrix.  [electronic resource] 

 -  Clinical cancer research : an official journal of the American Association for Cancer Research  Jun 2006 
 - 3470-7 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1078-0432 
<br/><br/><label>Standard No.: </label>10.1158/1078-0432.CCR-06-0361  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antibodies, Monoclonal--immunology<br/>Antigen-Antibody Reactions<br/>Binding Sites<br/>Carcinoma, Renal Cell--drug therapy<br/>Cell Cycle--drug effects<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cyclin-Dependent Kinase 2--metabolism<br/>Cyclin-Dependent Kinase Inhibitor p27--biosynthesis<br/>Dipeptidyl Peptidase 4--biosynthesis<br/>Dipeptidyl-Peptidase IV Inhibitors<br/>Disease Models, Animal<br/>Dose-Response Relationship, Drug<br/>Drug Screening Assays, Antitumor<br/>Extracellular Matrix--drug effects<br/>Female<br/>G1 Phase--drug effects<br/>Humans<br/>Kidney Neoplasms--drug therapy<br/>Mice<br/>Mice, Inbred BALB C<br/>Mice, Nude<br/>Phosphorylation--drug effects<br/>Retinoblastoma Protein--metabolism<br/>S Phase--drug effects<br/>Structure-Activity Relationship<br/>Transplantation, Heterologous<br/>Xenograft Model Antitumor Assays