TY - GEN AU - Qi,Huiling AU - Ratnam,Manohar TI - Synergistic induction of folate receptor beta by all-trans retinoic acid and histone deacetylase inhibitors in acute myelogenous leukemia cells: mechanism and utility in enhancing selective growth inhibition by antifolates SN - 0008-5472 PY - 2006///0727 KW - Acetylation KW - drug effects KW - Animals KW - Antineoplastic Combined Chemotherapy Protocols KW - pharmacology KW - Biomarkers, Tumor KW - metabolism KW - CHO Cells KW - Carrier Proteins KW - biosynthesis KW - Cricetinae KW - Drug Synergism KW - Enzyme Inhibitors KW - administration & dosage KW - Folate Receptors, GPI-Anchored KW - Folic Acid Antagonists KW - Histone Deacetylase Inhibitors KW - Histones KW - Humans KW - Hydroxamic Acids KW - Leukemia, Myeloid, Acute KW - drug therapy KW - Promoter Regions, Genetic KW - RNA, Messenger KW - Receptors, Cell Surface KW - Receptors, Immunologic KW - Receptors, Retinoic Acid KW - Substrate Specificity KW - Tetrahydrofolates KW - Transcription Factor AP-1 KW - Tretinoin KW - Up-Regulation KW - Valproic Acid N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1158/0008-5472.CAN-05-4048 ER -