Identification of new biomarkers for clinical trials of Hsp90 inhibitors. [electronic resource]
- Molecular cancer therapeutics May 2006
- 1256-64 p. digital
Publication Type: Journal Article
1535-7163
10.1158/1535-7163.MCT-05-0537 doi
Animals Antineoplastic Agents--pharmacology Benzoquinones Biomarkers, Tumor--chemistry Breast Neoplasms--drug therapy Clinical Trials, Phase I as Topic Dose-Response Relationship, Drug Down-Regulation Female HSP90 Heat-Shock Proteins--antagonists & inhibitors In Vitro Techniques Insulin-Like Growth Factor Binding Protein 2--blood Lactams, Macrocyclic Mice Mice, Nude Protein Structure, Tertiary--drug effects Receptor, ErbB-2--blood Rifabutin--analogs & derivatives Tumor Cells, Cultured Xenograft Model Antitumor Assays