Macrophage-colony-stimulating factor-induced proliferation and lipopolysaccharide-dependent activation of macrophages requires Raf-1 phosphorylation to induce mitogen kinase phosphatase-1 expression. [electronic resource]
- Journal of immunology (Baltimore, Md. : 1950) Jun 2006
- 6594-602 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
0022-1767
10.4049/jimmunol.176.11.6594 doi
Animals Cell Cycle--immunology Cell Cycle Proteins--biosynthesis Cell Proliferation Cells, Cultured Cytokines--biosynthesis Dual Specificity Phosphatase 1 Enzyme Induction--immunology Extracellular Signal-Regulated MAP Kinases--metabolism Immediate-Early Proteins--biosynthesis Lipopolysaccharides--pharmacology Macrophage Activation--immunology Macrophage Colony-Stimulating Factor--physiology Macrophages--cytology Mice Mice, Inbred BALB C Mitogen-Activated Protein Kinase 1--metabolism Mitogen-Activated Protein Kinase 3--metabolism Phosphoprotein Phosphatases--biosynthesis Phosphorylation Protein Kinase C-epsilon--metabolism Protein Phosphatase 1 Protein Tyrosine Phosphatases--biosynthesis Proto-Oncogene Proteins c-raf--antagonists & inhibitors