The phosphoinositide 3-kinase/Akt pathway: a new target in human renal cell carcinoma therapy. [electronic resource]
- Cancer research May 2006
- 5130-42 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0008-5472
10.1158/0008-5472.CAN-05-1469 doi
Animals Carcinoma, Renal Cell--drug therapy Cell Growth Processes--drug effects Cell Line, Tumor Chromones--pharmacology Enzyme Inhibitors--pharmacology Humans Kidney Neoplasms--drug therapy Male Mice Morpholines--pharmacology Oncogene Protein v-akt--antagonists & inhibitors Phosphatidylinositol 3-Kinases--metabolism Phosphoinositide-3 Kinase Inhibitors Phosphorylation--drug effects RNA, Small Interfering--genetics Signal Transduction Substrate Specificity Transfection Xenograft Model Antitumor Assays