Macgregor, Jennifer N <br/><br/>
Ex vivo culture with interleukin (IL)-12 improves CD8(+) T-cell adoptive immunotherapy for murine leukemia independent of IL-18 or IFN-gamma but requires perforin.  [electronic resource] 

 -  Cancer research  May 2006 
 - 4913-21 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0008-5472 
<br/><br/><label>Standard No.: </label>10.1158/0008-5472.CAN-05-3507  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acute Disease<br/>Animals<br/>CD8-Positive T-Lymphocytes--drug effects<br/>Cell Line, Tumor<br/>Cytotoxicity, Immunologic<br/>Drug Synergism<br/>Epitopes, T-Lymphocyte--immunology<br/>Female<br/>Immunotherapy, Adoptive--methods<br/>Interferon-gamma--deficiency<br/>Interleukin-12--immunology<br/>Interleukin-18--immunology<br/>Leukemia, Myeloid--immunology<br/>Lymphocyte Activation<br/>Male<br/>Membrane Glycoproteins--deficiency<br/>Mice<br/>Mice, Inbred BALB C<br/>Mice, Inbred C57BL<br/>Mice, Knockout<br/>Perforin<br/>Pore Forming Cytotoxic Proteins