TY - GEN AU - Griffith,David C AU - Corcoran,Erik AU - Lofland,Denene AU - Lee,Angela AU - Cho,Deidre AU - Lomovskaya,Olga AU - Dudley,Michael N TI - Pharmacodynamics of levofloxacin against Pseudomonas aeruginosa with reduced susceptibility due to different efflux pumps: do elevated MICs always predict reduced in vivo efficacy? SN - 0066-4804 PY - 2006///0609 KW - Animals KW - Anti-Bacterial Agents KW - blood KW - Area Under Curve KW - Bacterial Outer Membrane Proteins KW - genetics KW - Disease Models, Animal KW - Dose-Response Relationship, Drug KW - Drug Resistance, Bacterial KW - Gene Deletion KW - Genes, Bacterial KW - Levofloxacin KW - Male KW - Membrane Proteins KW - Membrane Transport Proteins KW - Mice KW - Microbial Sensitivity Tests KW - Neutropenia KW - microbiology KW - Ofloxacin KW - Pseudomonas aeruginosa KW - drug effects KW - Sepsis N1 - Publication Type: Journal Article UR - https://doi.org/10.1128/AAC.50.5.1628-1632.2006 ER -