The promoter region of the MDR1 gene is largely invariant, but different single nucleotide polymorphism haplotypes affect MDR1 promoter activity differently in different cell lines. [electronic resource]
- Molecular pharmacology Jul 2006
- 267-76 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
0026-895X
10.1124/mol.105.019810 doi
Black or African American--genetics Alleles Asian People--genetics Base Sequence Cell Line Cell Line, Tumor China DNA--chemistry DNA Mutational Analysis Gene Frequency Genes, MDR--genetics Haplotypes--genetics HeLa Cells Humans India Malaysia Molecular Sequence Data Polymorphism, Single Nucleotide--genetics Promoter Regions, Genetic--genetics White People--genetics