TY - GEN AU - Zhang,Han-Ting AU - Zhao,Yu AU - Huang,Ying AU - Deng,Chengjun AU - Hopper,Allen T AU - De Vivo,Michael AU - Rose,Gregory M AU - O'Donnell,James M TI - Antidepressant-like effects of PDE4 inhibitors mediated by the high-affinity rolipram binding state (HARBS) of the phosphodiesterase-4 enzyme (PDE4) in rats SN - 0033-3158 PY - 2006///1020 KW - 3',5'-Cyclic-AMP Phosphodiesterases KW - antagonists & inhibitors KW - Animals KW - Antidepressive Agents KW - pharmacology KW - Behavior, Animal KW - drug effects KW - Binding, Competitive KW - Cyclic Nucleotide Phosphodiesterases, Type 4 KW - Male KW - Phosphodiesterase Inhibitors KW - Radioligand Assay KW - Rats KW - Rats, Sprague-Dawley KW - Rolipram N1 - Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1007/s00213-006-0369-4 ER -