Zhang, Han-Ting

Antidepressant-like effects of PDE4 inhibitors mediated by the high-affinity rolipram binding state (HARBS) of the phosphodiesterase-4 enzyme (PDE4) in rats. [electronic resource] - Psychopharmacology Jun 2006 - 209-17 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural

0033-3158

10.1007/s00213-006-0369-4 doi


3',5'-Cyclic-AMP Phosphodiesterases--antagonists & inhibitors
Animals
Antidepressive Agents--pharmacology
Behavior, Animal--drug effects
Binding, Competitive
Cyclic Nucleotide Phosphodiesterases, Type 4
Male
Phosphodiesterase Inhibitors--pharmacology
Radioligand Assay
Rats
Rats, Sprague-Dawley
Rolipram--pharmacology