TY - GEN AU - Lazar,Greg A AU - Dang,Wei AU - Karki,Sher AU - Vafa,Omid AU - Peng,Judy S AU - Hyun,Linus AU - Chan,Cheryl AU - Chung,Helen S AU - Eivazi,Araz AU - Yoder,Sean C AU - Vielmetter,Jost AU - Carmichael,David F AU - Hayes,Robert J AU - Dahiyat,Bassil I TI - Engineered antibody Fc variants with enhanced effector function SN - 0027-8424 PY - 2006///0425 KW - Alemtuzumab KW - Animals KW - Antibodies, Monoclonal KW - genetics KW - Antibodies, Monoclonal, Humanized KW - Antibodies, Neoplasm KW - Antibody Affinity KW - Antibody Specificity KW - Antibody-Dependent Cell Cytotoxicity KW - Antineoplastic Agents KW - metabolism KW - B-Lymphocytes KW - immunology KW - Complement System Proteins KW - Cytotoxicity, Immunologic KW - Genetic Variation KW - Humans KW - Immunoglobulin Fc Fragments KW - In Vitro Techniques KW - Lymphocyte Depletion KW - Macaca fascicularis KW - Protein Engineering KW - Receptors, IgG KW - Trastuzumab N1 - Publication Type: Journal Article UR - https://doi.org/10.1073/pnas.0508123103 ER -