Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling. [electronic resource]
- The Journal of cell biology Mar 2006
- 909-21 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
0021-9525
10.1083/jcb.200508130 doi
Animals Bone Development--genetics Bone Neoplasms--genetics Cell Differentiation--genetics Cell Proliferation Cell Transformation, Neoplastic--genetics Cells, Cultured Core Binding Factor Alpha 1 Subunit--metabolism Gene Expression Regulation, Developmental--genetics Genetic Predisposition to Disease--genetics Mice Mice, Transgenic Osteoblasts--cytology Osteosarcoma--genetics Proto-Oncogene Proteins c-mdm2--genetics Signal Transduction--genetics Skeleton Stem Cells--cytology Tumor Suppressor Protein p53--genetics Up-Regulation--physiology