TY - GEN AU - Mathews,V AU - Desire,S AU - George,B AU - Lakshmi,K M AU - Rao,J G AU - Viswabandya,A AU - Bajel,A AU - Srivastava,V M AU - Srivastava,A AU - Chandy,M TI - Hepatotoxicity profile of single agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia, its impact on clinical outcome and the effect of genetic polymorphisms on the incidence of hepatotoxicity SN - 0887-6924 PY - 2006///0912 KW - Adult KW - Arsenic Trioxide KW - Arsenicals KW - administration & dosage KW - Chemical and Drug Induced Liver Injury KW - complications KW - Cohort Studies KW - Disease-Free Survival KW - Female KW - Follow-Up Studies KW - Genetic Predisposition to Disease KW - Humans KW - Incidence KW - Leukemia, Promyelocytic, Acute KW - diagnosis KW - Liver KW - drug effects KW - Liver Function Tests KW - Male KW - Methylenetetrahydrofolate Reductase (NADPH2) KW - genetics KW - Oxides KW - Polymorphism, Genetic KW - Remission Induction KW - Risk Factors KW - Survival Rate KW - Treatment Outcome N1 - Publication Type: Clinical Trial; Letter UR - https://doi.org/10.1038/sj.leu.2404165 ER -