Prediction of in vivo embryotoxic effect levels with a combination of in vitro studies and PBPK modelling. [electronic resource]
- Toxicology letters Aug 2006
- 79-87 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0378-4274
10.1016/j.toxlet.2006.01.017 doi
Animal Testing Alternatives Animals Cell Line Cell Survival--drug effects Dose-Response Relationship, Drug Embryo, Mammalian--drug effects Mice Models, Biological Predictive Value of Tests Rats Risk Assessment Stem Cells--cytology Teratogens--pharmacokinetics Toxicity Tests--methods