Faucette, Stephanie R

Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor. [electronic resource] - The Journal of pharmacology and experimental therapeutics Jun 2006 - 1200-9 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

0022-3565

10.1124/jpet.105.098160 doi


Aryl Hydrocarbon Hydroxylases--genetics
Base Sequence
Cell Line, Tumor
Constitutive Androstane Receptor
Cytochrome P-450 CYP2B6
Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme System--genetics
Electrophoretic Mobility Shift Assay
Gene Expression Regulation, Enzymologic--drug effects
Genes, Reporter
Hepatocytes--drug effects
Humans
Liver--drug effects
Molecular Sequence Data
Oxidoreductases, N-Demethylating--genetics
Oximes--pharmacology
Pregnane X Receptor
Protein Binding
Receptor Cross-Talk--physiology
Receptors, Cytoplasmic and Nuclear--agonists
Receptors, Steroid--agonists
Reverse Transcriptase Polymerase Chain Reaction
Rifampin--pharmacology
Thiazoles--pharmacology
Transcription Factors--agonists