TY - GEN AU - Maki,Nazli AU - Moitra,Karobi AU - Ghosh,Pratiti AU - Dey,Saibal TI - Allosteric modulation bypasses the requirement for ATP hydrolysis in regenerating low affinity transition state conformation of human P-glycoprotein SN - 0021-9258 PY - 2006///0613 KW - ATP Binding Cassette Transporter, Subfamily B KW - chemistry KW - ATP Binding Cassette Transporter, Subfamily B, Member 1 KW - metabolism KW - Adenosine Diphosphate KW - analogs & derivatives KW - Adenosine Triphosphate KW - Allosteric Site KW - Animals KW - Azides KW - Binding Sites KW - Catalytic Domain KW - Cell Line KW - Cell Membrane KW - Flupenthixol KW - Humans KW - Hydrolysis KW - Insecta KW - Ligands KW - Molecular Conformation KW - Prazosin KW - Protein Binding KW - Protein Conformation KW - Protein Structure, Tertiary KW - Thioxanthenes KW - Time Factors KW - Trypsin KW - Vanadates N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1074/jbc.M512579200 ER -