TY - GEN AU - Shitara,Yoshihisa AU - Horie,Toshiharu AU - Sugiyama,Yuichi TI - Transporters as a determinant of drug clearance and tissue distribution SN - 0928-0987 PY - 2006///0620 KW - ATP Binding Cassette Transporter, Subfamily B, Member 1 KW - genetics KW - Animals KW - Bile KW - metabolism KW - Carbamates KW - pharmacokinetics KW - Cell Line KW - Drug Interactions KW - Humans KW - Hydroxymethylglutaryl-CoA Reductase Inhibitors KW - Hypoglycemic Agents KW - Kidney KW - Liver KW - Membrane Transport Proteins KW - Metabolic Clearance Rate KW - Metformin KW - Organic Anion Transporters KW - Organic Cation Transport Proteins KW - Piperidines KW - Polymorphism, Genetic KW - Species Specificity KW - Tissue Distribution KW - Transfection N1 - Publication Type: Journal Article; Review UR - https://doi.org/10.1016/j.ejps.2005.12.003 ER -