Wang, Jeh-Jeng

Design, synthesis, and biological evaluation of pyrrolo[2,1-c][1,4]benzodiazepine and indole conjugates as anticancer agents. [electronic resource] - Journal of medicinal chemistry Feb 2006 - 1442-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-2623

10.1021/jm050956q doi


Antineoplastic Agents--chemical synthesis
Apoptosis
Benzodiazepines--chemical synthesis
Cell Cycle--drug effects
Cell Line, Tumor
DNA--chemistry
Drug Design
Drug Screening Assays, Antitumor
Humans
Indoles--chemical synthesis
Melanoma
Membrane Potentials--drug effects
Mitochondrial Membranes--drug effects
Models, Molecular
Pyrroles--chemical synthesis
Structure-Activity Relationship