TY  - GEN
AU  - Manno,Catherine S
AU  - Pierce,Glenn F
AU  - Arruda,Valder R
AU  - Glader,Bertil
AU  - Ragni,Margaret
AU  - Rasko,John J
AU  - Rasko,John
AU  - Ozelo,Margareth C
AU  - Hoots,Keith
AU  - Blatt,Philip
AU  - Konkle,Barbara
AU  - Dake,Michael
AU  - Kaye,Robin
AU  - Razavi,Mahmood
AU  - Zajko,Albert
AU  - Zehnder,James
AU  - Rustagi,Pradip K
AU  - Nakai,Hiroyuki
AU  - Chew,Amy
AU  - Leonard,Debra
AU  - Wright,J Fraser
AU  - Lessard,Ruth R
AU  - Sommer,Jürg M
AU  - Tigges,Michael
AU  - Sabatino,Denise
AU  - Luk,Alvin
AU  - Jiang,Haiyan
AU  - Mingozzi,Federico
AU  - Couto,Linda
AU  - Ertl,Hildegund C
AU  - High,Katherine A
AU  - Kay,Mark A
TI  - Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response
SN  - 1078-8956
PY  - 2006///0517
KW  - Adult
KW  - Amino Acid Sequence
KW  - Animals
KW  - Dependovirus
KW  - genetics
KW  - Dogs
KW  - Dose-Response Relationship, Drug
KW  - Exons
KW  - Factor IX
KW  - Genetic Therapy
KW  - Genetic Vectors
KW  - administration & dosage
KW  - Hemophilia A
KW  - Humans
KW  - Interferon-gamma
KW  - metabolism
KW  - Introns
KW  - Liver
KW  - immunology
KW  - Male
KW  - Mice
KW  - Middle Aged
KW  - Molecular Sequence Data
KW  - Monocytes
KW  - Transduction, Genetic
N1  - Publication Type: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/nm1358
ER  -